Beclin 1 (BECN1) Human shRNA Plasmid Kit (Locus ID 8678)
Specifications
| Product Data | |
| Locus ID | 8678 |
|---|---|
| Synonyms | ATG6; beclin1; VPS30 |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | BECN1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 8678). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_001313998, NM_001313999, NM_001314000, NM_003766, NM_003766.1, NM_003766.2, NM_003766.3, NM_003766.4, BC010276, BC010276.1 |
| UniProt ID | Q14457 |
| Summary | This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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