NALP12 (NLRP12) (NM_144687) Human Recombinant Protein

SKU TP762624

Purified recombinant protein of Human NLR family, pyrin domain containing 12 (NLRP12), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E.coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of NLRP12
• Tag: N-GST and C-HIS
• Predicted MW: 120.2 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_653288
• Locus ID: 91662
• UniProt ID: P59046
• Cytogenetics: 19q13.42
• RefSeq Size: 3880
• RefSeq ORF: 3183
• Synonyms: CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2
• Summary: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]