Rapsyn (RAPSN) (NM_032645) Human Recombinant Protein

SKU TP762566

Purified recombinant protein of Human receptor-associated protein of the synapse (RAPSN), transcript variant 2, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of RAPSN
• Tag: N-GST and C-HIS
• Predicted MW: 39.9 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_116034
• Locus ID: 5913
• UniProt ID: Q13702 A0A0S2Z4M9 Q13702-2
• Cytogenetics: 11p11.2
• RefSeq Size: 1494
• RefSeq ORF: 1059
• Synonyms: CMS4C; CMS11; FADS; FADS2; RAPSYN; RNF205
• Summary: This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2011]
• Protein Families: Druggable Genome