Fc epsilon RI (FCER1A) (NM_002001) Human Recombinant Protein

SKU TP762469

Purified recombinant protein of Human Fc fragment of IgE, high affinity I, receptor for, alpha polypeptide (FCER1A), Val26-End, with N-terminal His tag, expressed in E.coli, 50ug

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Val26-End) of FCER1A
• Tag: N-His
• Predicted MW: 27.0 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_001992
• Locus ID: 2205
• UniProt ID: P12319
• Cytogenetics: 1q23.2
• RefSeq Size: 1198
• RefSeq ORF: 771
• Synonyms: FCE1A; FcERI
• Summary: The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
• Protein Families: Transmembrane
• Protein Pathways: Asthma, Fc epsilon RI signaling pathway