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Cystatin C (CST3) (NM_000099) Human Recombinant Protein

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SKU
TP721238
Purified recombinant protein of Human cystatin C (CST3)
Size:
10 ug
  $340.00
5 Days*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Ser27-Ala146
Tag C-His
Predicted MW 14.4 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 10mM PB, 200mM NaCl, pH 6.5
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_000090
Locus ID 1471
UniProt ID P01034
Cytogenetics 20p11.21
RefSeq Size 929
RefSeq ORF 438
Synonyms ARMD11; HEL-S-2
Summary The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein. provided by RefSeq, Nov 2014
Protein Categories Nervous system: Neurodegenerative diseases, Secreated Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
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Other "Cystatin C" proteins (5)
SKU Description Size Price
PH310730 CST3 MS Standard C13 and N15-labeled recombinant protein (NP_000090) 10 ug
$3,360.00
LC400040 Lyophilized CST3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400040 Transient overexpression lysate of cystatin C (CST3) (as WB positive control) 100 ug
$436.00
TP310730 Recombinant protein of human cystatin C (CST3), 20 µg 20 ug
$737.00
TP721134 Purified recombinant protein of Human cystatin C (CST3) 10 ug
$275.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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