GI24 (C10orf54) (NM_022153) Human Recombinant Protein

SKU TP700219

Purified recombinant protein of Human B7H5 (B7H5), with C-terminal Fc tag, expressed in human cells

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, [RC204547], encoding the extracellular domain (Phe33-Ala194) of human B7H5
• Tag: C-Fc
• Predicted MW: 45 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: PBS, pH 7.4, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_071436
• Locus ID: 64115
• UniProt ID: Q9H7M9
• Cytogenetics: 10q22.1
• RefSeq Size: 4774
• RefSeq ORF: 933
• Synonyms: B7-H5; B7H5; C10orf54; DD1alpha; Dies1; GI24; PD-1H; PP2135; SISP1; VISTA
• Summary: Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation (PubMed:20666777).[UniProtKB/Swiss-Prot Function]
• Protein Families: Transmembrane