GI24 (C10orf54) Mouse Monoclonal Antibody [Clone ID: 4C4]
Product Data | |
Clone Name | 4C4 |
---|---|
Application | ELISA, FC, IF, IHC, WB |
Recommended Dilution | WB start at 0.25 - 1 ug/mL. IHC start at 2 ug/mL. ICC start at 1 ug/mL. IF start at 2 ug/mL. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | VISTA antibody was raised against the extracellular domain of human VISTA. |
Buffer | VISTA Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | VISTA Antibody is supplied as protein A purified IgG1. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | Predicted: 31 kDa; Observed: 47 kDa |
Gene Name | chromosome 10 open reading frame 54 |
Database Link | |
Background | VISTA Antibody: VISTA/B7-H5/platelet receptor Gi24 is a single-pass type I membrane protein located at the cell surface. It is an immunoregulatory receptor which can inhibit T-cell response and may promote differentiation of embryonic stem cells, by inhibiting the BMP4 signaling pathway. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. |
Synonyms | GI24; PP2135; SISP1 |
Reference Data |
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