Klhl13 (NM_026167) Mouse Recombinant Protein

SKU TP509669

Purified recombinant protein of Mouse kelch-like 13 (Klhl13), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  >MR209669 representing NM_026167; Red=Cloning site Green=Tags(s); ; MDILHRGELVAAILRNRSLVEEEDQHLKLCLGSEMGLSSHLQSCKAGSTRIFTSNSHSSVVLQGFDQLRL; DGLLCDVTLMPGDTDDAYPVHRVMMASASDYFKAMFTGGMKEQELMCIKLHGVSRVGLRKIIDFIYTAKL; SLNMDTLQDTLEAASFLQILPVLDFCKVFLISGVTLDNCVEVGRIANTYHLTEVDKYVNSFVLKNFAALL; STGEFLKLPFERLAFVLSSNSLKRCTELDLFKATCRWLRLEEPRMDVAAKLMKNIRFPLMTPQELINYVQ; TVDFMRTDNTCVNLLLEASNYQMMPFMQPVMQSDRTAIRSDTTRLVTLGGVLRQQLVVSKELRMYDEKTH; EWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWIQVASLNEKRTFFHLS; ALKGFLYAVGGRNAAGELPTVECYNPRTNEWTYVAKMNEPHYGHAGTVYGGVMYISGGITHDTFQKELMC; FDPDTDKWTQKAPMTTVRGLHCMCTVGDRLYVIGGNHFRGTSDYDDVLSCEYYSPILDQWTPIASMLRGQ; SDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKNEWHKVFDLPESLGGIRACTLTVYPPEEATPSPS; RESPLSGP; ; TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Tag: C-MYC/DDK
• Predicted MW: 72.5 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_080443
• Locus ID: 67455
• UniProt ID: Q80TF4
• Cytogenetics: X A2
• RefSeq Size: 3222
• RefSeq ORF: 1914
• Synonyms: 1200009K10Rik; AI451128; Bklhd2; D130072F20Rik
• Summary: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis (By similarity).[UniProtKB/Swiss-Prot Function]