Stxbp4 (BC032881) Mouse Recombinant Protein

SKU TP508536

Purified recombinant protein of Mouse syntaxin binding protein 4 (cDNA clone MGC:41138 IMAGE:1224878), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  >MR208536 protein sequence; Red=Cloning site Green=Tags(s); ; MSDGTASARSSSPLDRDPAFRVITVTKETGLGLKILGGINRNEGPLVYIHEVIPGGDCYKDGRLKPGDQL; VSINKESMIGVSFEEAKSIITRAKLRSESPWEIAFIRQKSYCGHPGNICCPSPQVSEDCGPQTSTFTLLS; SPSETLLPKTSSTPQTQDSTFPSCKAIQTKPEHDKTEHSPITSLDNSPADTSNADIAPAWTDDDSGPQGK; ISLNPSVRLKAEKLEMALNYLGIQPTKEQREALREQVQADSKGTVSFGDFVQVARSLFCLQLDEVNVGVH; EIPSILDSQLLPCDSLEADEVGKLRQERNAALEERNVLKEKLLESEKHRKQLIEELQNVKQEAKAVAEET; RALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAEVSELKAQLADYSDQNKESVQDLRKRVTVLDCQLRKS; EMARKAFKASTERLLGFIEAIQEVLLDSSAPLSTLSERRAVLASQTSLPLLARNGRSFPATLLLESKELV; RSVRAILDMDCKLSLSSSSSPSSSSSFSSSSSCNLLNKAEERP; ; TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Tag: C-MYC/DDK
• Predicted MW: 58.6 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• Locus ID: 20913
• UniProt ID: Q9WV89
• Cytogenetics: 11 D
• RefSeq Size: 1807
• RefSeq ORF: 1600
• Synonyms: 6030470M02Rik; Synip
• Summary: Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.[UniProtKB/Swiss-Prot Function]