Riox2 (NM_025910) Mouse Recombinant Protein

SKU TP507428

Purified recombinant protein of Mouse ribosomal oxygenase 2 (Riox2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  >MR207428 protein sequence; Red=Cloning site Green=Tags(s); ; MPKKVQPTGDENEEESVPCKRVKEELPETLSVLNFDSPSSFFESLISPIKVETFFKEFWEQKPLLIQRDD; PVLAKYYQSLFSLSDLKRLCKKGVYYGRDVNVCRSISGKKKVLNKDGRAHFLQLRKDFDQKRATIQFHQP; QRYKDELWRIQEKLECYFGSLVGSNVYMTPAGSQGLPPHYDDVEVFILQLEGTKHWRLYSPTVPLAHEYS; VESEDRIGTPTHDFLLKPGDLLYFPRGTIHQAETPSGLAYSIHLTISTYQNNSWGDCLLDSISGFVFDIA; KEDVALRSGMPRRMLLNVETPADVTRKLSGFLRTLADQLEGREELLSSDMKKDFVKHRLPPFFEGNGTET; MDPGKQLPRLDNIIRLQFKDHIVLTVGPDKNPFDEAQQKVVYIYHSLKNVRQMHMIGEEEESEIFGLRFP; LSHVDALKQIWCGSPIRVKELKLDTDEEKENLALSLWSESLIQVL; ; TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Tag: C-MYC/DDK
• Predicted MW: 53.6 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_080186
• Locus ID: 67014
• UniProt ID: Q8CD15
• Cytogenetics: 16 C1.3
• RefSeq Size: 2159
• RefSeq ORF: 1395
• Synonyms: 1810047J07Rik; 2410057H13Rik; 3830408E23Rik; AI449204
• Summary: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39' (By similarity). May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.[UniProtKB/Swiss-Prot Function]