MASPIN (SERPINB5) (NM_002639) Human Recombinant Protein

SKU TP324287

Recombinant protein of human serpin peptidase inhibitor, clade B (ovalbumin), member 5 (SERPINB5), 20 µg

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  >RC224287 representing NM_002639; Red=Cloning site Green=Tags(s); ; MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGF; QTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLT; DGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFPESETKECPFRVNKTDTKPVQMMNMEATFCMGNID; SINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEK; MIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVVHKVCLEITEDGGDSIEVPGARILQHKDELNA; DHPFIYIIRHNKTRNIIFFGKFCSP; ; TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Tag: C-Myc/DDK
• Predicted MW: 41.9 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_002630
• Locus ID: 5268
• UniProt ID: P36952
• Cytogenetics: 18q21.33
• RefSeq Size: 2558
• RefSeq ORF: 1125
• Synonyms: maspin; PI5
• Summary: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.[UniProtKB/Swiss-Prot Function]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: p53 signaling pathway