Rab11 (RAB11B) (NM_004218) Human Recombinant Protein

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SKU
TP322162
Recombinant protein of human RAB11B, member RAS oncogene family (RAB11B), 20 µg
  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC222162 protein sequence
Red=Cloning site Green=Tags(s)

MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQ
ERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEAR
AFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNVVDISVPPTTDGQKPN
KLQCCQNL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 24.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_004209
Locus ID 9230
UniProt ID Q15907
Cytogenetics 19p13.2
RefSeq Size 1635
RefSeq ORF 654
Synonyms H-YPT3; NDAGSCW
Summary The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 PubMed 7811277).supplied by OMIM, Nov 2010
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Endocytosis
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Other "Rab11" proteins (3)
SKU Description Size Price
PH322162 RAB11B MS Standard C13 and N15-labeled recombinant protein (NP_004209) 10 ug
$3,360.00
LC418145 Lyophilized RAB11B HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418145 Transient overexpression lysate of RAB11B, member RAS oncogene family (RAB11B) (as WB positive control) 100 ug
$436.00

file-alt Citations

RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells
Joseph, Flores, Farrell et al
EMBO Rep (2023)
Cited by 15
AI Summary: OriGene’s recombinant Rab11a (TP300352) and Rab11b (TP322162) proteins were used in binding assays to investigate the protein interactions underlying mitotic spindle regulation in intestinal epithelial progenitor cells.
Snippet: For binding, individual TnT reactions were added to 300 ng of Rab11a (Origene, TP300352) or Rab11b (Origene, TP322162) recombinant proteins immobilized on
Showing 1-1 of 1 papers.
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