PLA1A (NM_015900) Human Recombinant Protein

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SKU
TP319486
Purified recombinant protein of Homo sapiens phospholipase A1 member A (PLA1A), 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC219486 representing NM_015900
Red=Cloning site Green=Tags(s)

MPPGPWESCFWVGGLILWLSVGSSGDAPPTPQPKCADFQSANLFEGTDLKVQFLLFVPSNPSCGQLVEGS
SDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNANVIAVDWIYGSTGVYFSAVKNVIKLS
LEISLFLNKLLVLGVSESSIHIIGVSLGAHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEERLDAGDA
LFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPTFFYAGYSYLICDHMRAVHLYISALENSCPLMAF
PCASYKAFLAGRCLDCFNPFLLSCPRIGLVEQGGVKIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKEL
RNKDTNIEVTFLSSNITSSSKITIPKQQRYGKGIIAHATPQCQINQVKFKFQSSNRVWKKDRTTIIGKFC
TALLPVNDREKMVCLPEPVNLQASVTVSCDLKIACV

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 49.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_056984
Locus ID 51365
UniProt ID Q53H76
Cytogenetics 3q13.33
RefSeq Size 1758
RefSeq ORF 1368
Synonyms PS-PLA1; PSPLA1
Summary The protein encoded by this gene is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine in liposomes. Three transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, May 2011
Protein Categories Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
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Other "PLA1A" proteins (3)
SKU Description Size Price
PH319486 PLA1A MS Standard C13 and N15-labeled recombinant protein (NP_056984) 10 ug
$3,360.00
LC414332 Lyophilized PLA1A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY414332 Transient overexpression lysate of phospholipase A1 member A (PLA1A) (as WB positive control) 100 ug
$665.00

file-alt Citations

Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis
Zhao, Hasse, Vaillancourt et al
Int J Mol Sci (2021) 22 (23) DOI: 10.3390/ijms222312685
Cited by 11
AI Summary: OriGene’s recombinant human PLA1A protein (Cat# TP321482) was used to stimulate primary fibroblast-like synoviocytes, enabling the authors to demonstrate PLA1A’s role in inducing pro-inflammatory responses via the autotaxin-lysophosphatidic acid receptor axis.
FigureFigureFigure
Showing 1-1 of 1 papers.
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