PYK2 (PTK2B) (NM_173175) Human Recombinant Protein
SKU
TP317684
Recombinant protein of human PTK2B protein tyrosine kinase 2 beta (PTK2B), transcript variant 4, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 111 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_775267 |
| Locus ID | 2185 |
| UniProt ID | Q14289 |
| Cytogenetics | 8p21.2 |
| RefSeq Size | 3936 |
| RefSeq ORF | 2901 |
| Synonyms | CADTK; CAKB; FADK2; FAK2; PKB; PTK; PYK2; RAFTK |
| Summary | This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. provided by RefSeq, Jul 2008 |
| Protein Categories | Chemokines, Enzyme: Kinases, Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Calcium signaling pathway, Chemokine signaling pathway, GnRH signaling pathway, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PYK2" proteins (11)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH303808 | PTK2B MS Standard C13 and N15-labeled recombinant protein (NP_004094) | 10 ug |
$3,360.00
|
|
| PH305372 | PTK2B MS Standard C13 and N15-labeled recombinant protein (NP_775266) | 10 ug |
$3,360.00
|
|
| PH317684 | PTK2B MS Standard C13 and N15-labeled recombinant protein (NP_775267) | 10 ug |
$3,360.00
|
|
| LC401325 | Lyophilized PTK2B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC406631 | Lyophilized PTK2B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC406632 | Lyophilized PTK2B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401325 | Transient overexpression lysate of PTK2B protein tyrosine kinase 2 beta (PTK2B), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY406631 | Transient overexpression lysate of PTK2B protein tyrosine kinase 2 beta (PTK2B), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY406632 | Transient overexpression lysate of PTK2B protein tyrosine kinase 2 beta (PTK2B), transcript variant 4 (as WB positive control) | 100 ug |
$665.00
|
|
| TP303808 | Recombinant protein of human PTK2B protein tyrosine kinase 2 beta (PTK2B), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
| TP305372 | Recombinant protein of human PTK2B protein tyrosine kinase 2 beta (PTK2B), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
