TAPA1 (CD81) (NM_004356) Human Recombinant Protein

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human CD81 molecule (CD81)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 25.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity ELISA standard (PMID: 27408937)
ELISA standard (PMID: 27511944)
ELISA standard (PMID: 27601437)
ELISA standard (PMID: 28105773)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_004347
Locus ID 975
Refseq Size 1497
Cytogenetics 11p15.5
Refseq ORF 708
Synonyms CVID6; S5.7; TAPA1; TSPAN28
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways B cell receptor signaling pathway

Citations (7)

Documents

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