ROR1 (NM_005012) Human Recombinant Protein
SKU
TP314967
Recombinant protein of human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1, 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 104.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | ELISA capture for autoantibodies (PMID: 26562161) WB positive control (PMID: 26562161) Affinity purification chromatography (PMID: 26562161) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_005003 |
| Locus ID | 4919 |
| UniProt ID | Q01973 |
| Cytogenetics | 1p31.3 |
| RefSeq Size | 3358 |
| RefSeq ORF | 2811 |
| Synonyms | dJ537F10.1; NTRKR1 |
| Summary | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jun 2012 |
| Protein Categories | ADC Targets, CAR-T Targets, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "ROR1" proteins (11)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH314967 | ROR1 MS Standard C13 and N15-labeled recombinant protein (NP_005003) | 10 ug |
$3,360.00
|
|
| PH324765 | ROR1 MS Standard C13 and N15-labeled recombinant protein (NP_001077061) | 10 ug |
$3,360.00
|
|
| LC401558 | Lyophilized ROR1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC421225 | Lyophilized ROR1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401558 | Transient overexpression lysate of receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY421225 | Transient overexpression lysate of receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP324765 | Recombinant protein of human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
| TP700158 | Purified recombinant protein of Homo sapiens receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1, residue 30-406 aa, expressed in HEK293 cells. | 20 ug |
$900.00
|
|
| TP700159 | Purified recombinant protein of Human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 2, with C-terminal DDK/His tag, expressed in human cells | 20 ug |
$900.00
|
|
| TP700184 | Purified recombinant protein of Homo sapiens receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1, residue 30-406 aa, expressed in HEK293 cells, with Fc tag | 20 ug |
$900.00
|
|
| TP762391 | Purified recombinant protein of Human receptor tyrosine kinase-like orphan receptor 1 (ROR1), transcript variant 1, Gln30-Tyr406, with N-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$260.00
|
|
Citations
Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia
Hojjat-Farsangi, Jeddi-Tehrani, Daneshmanesh et al
PLoS ONE (2015) 10 (11), e0142310 DOI: 10.1371/journal.pone.0142310
Hojjat-Farsangi, Jeddi-Tehrani, Daneshmanesh et al
PLoS ONE (2015) 10 (11), e0142310 DOI: 10.1371/journal.pone.0142310
Cited by 15
AI Summary: OriGene’s full-length recombinant ROR1 protein was used in this study for Western blot analysis to detect anti-ROR1 antibodies in patient samples, contributing to the assessment of spontaneous immunity against ROR1 in CLL patients.
Snippet: A full length recombinant ROR1 protein (OriGene Technologies, Rockville, MD, USA) and a recombinant KNG domain (Protein Abnova Corporation, Taipei, Taiwan) respectively as well as immunoprecipitated ROR1 protein from CLL cell lysates were used in Western ... Cite SaveSaving
Showing 1-1 of 1 papers.
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