Thrombospondin 1 (THBS1) (NM_003246) Human Recombinant Protein

CAT#: TP314802

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Recombinant protein of human thrombospondin 1 (THBS1)

 Product Datasheet for 'TP314802'

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USD 788.00

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    • 20 ug

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Product Data
Description Recombinant protein of human thrombospondin 1 (THBS1)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 127.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_003237
Locus ID 7057
Refseq Size 5820
Cytogenetics 15q14
Refseq ORF 3510
Synonyms THBS; THBS-1; TSP; TSP-1; TSP1
Summary The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Bladder cancer, ECM-receptor interaction, Focal adhesion, p53 signaling pathway, TGF-beta signaling pathway


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