PLA2G10 (NM_003561) Human Recombinant Protein

CAT#: TP313014

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Recombinant protein of human phospholipase A2, group X (PLA2G10)


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USD 748.00


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    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human phospholipase A2, group X (PLA2G10)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 18 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_003552
Locus ID 8399
Refseq Size 1020
Cytogenetics 16p13.12
Refseq ORF 495
Synonyms GXPLA2; GXSPLA2; SPLA2; sPLA2-X
Summary This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. [provided by RefSeq, Nov 2015]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway

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68 Mouse Clones
HUMAN PROREINS 101