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HNF1 alpha (HNF1A) (NM_000545) Human Recombinant Protein

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SKU
TP311201
Recombinant protein of human HNF1 homeobox A (HNF1A), 20 µg
Size:
20 ug 1 mg 100 ug
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  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC211201 representing NM_000545
Red=Cloning site Green=Tags(s)

MVSKLSQLQTELLAALLESGLSKEALLQALGEPGPYLLAGEGPLDKGESCGGGRGELAELPNGLGETRGS
EDETDDDGEDFTPPILKELENLSPEEAAHQKAVVETLLQEDPWRVAKMVKSYLQQHNIPQREVVDTTGLN
QSHLSQHLNKGTPMKTQKRAALYTWYVRKQREVAQQFTHAGQGGLIEEPTGDELPTKKGRRNRFKWGPAS
QQILFQAYERQKNPSKEERETLVEECNRAECIQRGVSPSQAQGLGSNLVTEVRVYNWFANRRKEEAFRHK
LAMDTYSGPPPGPGPGPALPAHSSPGLPPPALSPSKVHGVRYGQPATSETAEVPSSSGGPLVTVSTPLHQ
VSPTGLEPSHSLLSTEAKLVSAAGGPLPPVSTLTALHSLEQTSPGLNQQPQNLIMASLPGVMTIGPGEPA
SLGPTFTNTGASTLVIGLASTQAQSVPVINSMGSSLTTLQPVQFSQPLHPSYQQPLMPPVQSHVTQSPFM
ATMAQLQSPHALYSHKPEVAQYTHTGLLPQTMLITDTTNLSALASLTPTKQVFTSDTEASSESGLHTPAS
QATTLHVPSQDPAGIQHLQPAHRLSASPTVSSSSLVLYQSSDSSNGQSHLLPSNHSVIETFISTQMASSS
Q

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 67.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000536
Locus ID 6927
UniProt ID P20823
Cytogenetics 12q24.31
RefSeq Size 3249
RefSeq ORF 1893
Synonyms HNF-1A; HNF1; HNF1alpha; HNF4A; IDDM20; LFB1; MODY3; TCF-1; TCF1
Summary The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015
Protein Categories Cancer: Bladder, Diabetes, Intracellular Proteins
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
Protein Pathways Maturity onset diabetes of the young
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Documents
Resources
Other "HNF1 alpha" proteins (6)
SKU Description Size Price
PH311201 HNF1A MS Standard C13 and N15-labeled recombinant protein (NP_000536) 10 ug
$3,360.00
LC400185 HNF1A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400185 Transient overexpression lysate of HNF1 homeobox A (HNF1A) 100 ug
$436.00
TP701007 Purified recombinant protein of Human HNF1 homeobox A (HNF1A), mutant (C236S), expressed in HEK293 cells, 20ug 20 ug
$900.00
TP701008 Purified recombinant protein of Human HNF1 homeobox A (HNF1A), mutant (C241S), expressed in HEK293 cells, 20ug 20 ug
$900.00
TP701027 Purified recombinant protein of Human HNF1 homeobox A (HNF1A), mutant (C50S), expressed in HEK293 cells, 20ug 20 ug
$900.00
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