PD1 (PDCD1) (NM_005018) Human Recombinant Protein
$2,508.00
5 Days*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 29.2 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_005009 |
| Locus ID | 5133 |
| UniProt ID | Q15116 |
| Cytogenetics | 2q37.3 |
| RefSeq Size | 2115 |
| RefSeq ORF | 864 |
| Synonyms | CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2 |
| Summary | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. provided by RefSeq, Aug 2020 |
| Protein Categories | ADC Targets, Allergies and autoimmune diseases, CD Markers, Intracellular Proteins, Membrane Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), T cell receptor signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
Tumor-derived extracellular vesicle PD-1 promotes tumor immune evasion via disruption of peripheral T cell homeostasis
Wang, Yang, Huang et al
Cancer Lett (2025) 612, 217486 DOI: 10.1016/j.canlet.2025.217486
Wang, Yang, Huang et al
Cancer Lett (2025) 612, 217486 DOI: 10.1016/j.canlet.2025.217486
Cited by 14
AI Summary: OriGene’s recombinant human PD-1 protein (CAT #: TP310364) was used to generate a standard curve for ELISA assays, enabling accurate quantification of PD-1 levels in the study.
Snippet: … The plates were read at 450 nm with a BioTek plate reader. Recombinant human PD-1 protein (Origene, CAT #: TP310364) was used to make a standard curve. …
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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