KLF2 (NM_016270) Human Recombinant Protein

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SKU
TP310042L
Recombinant protein of human Kruppel-like factor 2 (lung) (KLF2), 1 mg
  $7,820.00
6 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC210042 protein sequence
Red=Cloning site Green=Tags(s)

MALSEPILPSFSTFASPCRERGLQERWPRAEPESGGTDDDLNSVLDFILSMGLDGLGAEAAPEPPPPPPP
PAFYYPEPGAPPPYSAPAGGLVSELLRPELDAPPGPALHGRFLLAPPGRLVKAEPPEADGGGGYGCAPGL
TRGPRGLKREGAPGPAASCMRGPGGRPPPPPDTPPLSPDGPARLPAPGPRASFPPPFGGPGFGAPGPGLH
YAPPAPPAFGLFDDAAAAAAALGLAPPAARGLLTPPASPLELLEAKPKRGRRSWPRKRTATHTCSYAGCG
KTYTKSSHLKAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALH
MKRHM

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 37.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_057354
Locus ID 10365
UniProt ID Q9Y5W3
Cytogenetics 19p13.11
RefSeq Size 1655
RefSeq ORF 1065
Synonyms LKLF
Summary This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is expressed early in mammalian development and is found in many different cell types. The protein acts to bind the CACCC box found in the promoter of target genes to activate their transcription. It plays a role in many processes during development and disease including adipogenesis, embryonic erythropoiesis, epithelial integrity, inflammation and t-cell viability. provided by RefSeq, Mar 2017
Protein Categories Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Transcription Factors
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Documents
Resources

file-alt Citations

Transcription factor collaboration enables precise T cell state engineering
Savage, McRoberts Amador, Hock et al
bioRxiv (2026)
Cited by 2
AI Summary: OriGene’s KLF2 (TP310042) and RUNX2 (TP760214) proteins were used in vitro to study their collaborative effects on DNA binding and chromatin accessibility, contributing key mechanistic insights into transcription factor interactions that regulate CD8+ T cell states.
Snippet: KLF2 (OriGene, TP310042) and RUNX2 (OriGene,TP760214) were incubated both separately and together with 25ng of naked BAC DNA (RP11-82D16) in a 22.5 uL volume of water and tagmentation buffer (20 mM Tris, 10 mM MgCl2 and 20% dimethylformamide). …
Showing 1-1 of 1 papers.
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