LDHA (NM_005566) Human Recombinant Protein

CAT#: TP309378

Recombinant protein of human lactate dehydrogenase A (LDHA), transcript variant 1

Bulk Request/Custom Protein Development

 Product Datasheet for 'TP309378'

USD 680.00

In Stock

    • 20 ug

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Product Data
Description Recombinant protein of human lactate dehydrogenase A (LDHA), transcript variant 1
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC209378. Click on the TrueORF clone link to view cDNA and protein sequences.
Predicted MW 36.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at –80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Bioactivity Higher specific activity than endogenous human LDHA: OriGene human recombinant LDHA (TP309378) was compared side-by-side with purified human liver LDH5 in a spectrophotometric pyruvate to lactate conversion assay. Activity is shown as a decrease in absorbance at 340nm over time. The activity of recombinant human LDHA is comparable to that of endogenously expressed human LDH5.
Reference Data
RefSeq NP_005557
Locus ID 3939
Refseq Size 1661
Cytogenetics 11p15.1
Refseq ORF 996
Synonyms GSD11; HEL-S-133P; LDHM; PIG19
Summary The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008].
Protein Families
Protein Pathways
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