GPNMB (NM_001005340) Human Recombinant Protein
SKU
TP307615
Recombinant protein of human glycoprotein (transmembrane) nmb (GPNMB), transcript variant 1, 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 61.5 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | Pull-down assay (PMID: 26751287) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001005340 |
| Locus ID | 10457 |
| UniProt ID | Q14956 |
| Cytogenetics | 7p15.3 |
| RefSeq Size | 2775 |
| RefSeq ORF | 1716 |
| Synonyms | HGFIN; NMB; PLCA3 |
| Summary | The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008 |
| Protein Categories | ADC Targets, Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "GPNMB" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH307615 | GPNMB MS Standard C13 and N15-labeled recombinant protein (NP_001005340) | 10 ug |
$3,360.00
|
|
| LC400379 | Lyophilized GPNMB HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400379 | Transient overexpression lysate of glycoprotein (transmembrane) nmb (GPNMB), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP720414 | Recombinant protein of human glycoprotein (transmembrane) nmb (GPNMB), transcript variant 1 | 10 ug |
$235.00
|
|
Citations
The LINK-A lncRNA activates normoxic HIF1 [alpha] signalling in triple-negative breast cancer
Lin, Li, Xing et al
Nature cell biology (2016)
Lin, Li, Xing et al
Nature cell biology (2016)
Snippet: Yang and colleagues identify a lncRNA that controls HIF1[alpha] signalling to stabilize HIF1[alpha] under normoxic conditions, and promotes breast cancer tumorigenesis. Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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