Glutamine Synthetase(GLUL) (NM_002065) Human Recombinant Protein

CAT#: TP304161

Recombinant protein of human glutamate-ammonia ligase (glutamine synthetase) (GLUL), transcript variant 1


 Product Datasheet for 'TP304161'

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USD 748.00


Availability*
3 Weeks

Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human glutamate-ammonia ligase (glutamine synthetase) (GLUL), transcript variant 1
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC204161. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-MYC/DDK
Predicted MW 41.9 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at –80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_002056
Locus ID 2752
Refseq Size 4737
Cytogenetics 1q25.3
Refseq ORF 1122
Synonyms GLNS; GS; PIG43; PIG59
Summary The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Protein Pathways Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Nitrogen metabolism, Metabolic pathways

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Other Versions

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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