HSD17B2 (NM_002153) Human Recombinant Protein

  • Product Brand Image
SKU
TP303293
Recombinant protein of human hydroxysteroid (17-beta) dehydrogenase 2 (HSD17B2), 20 µg
  $867.00
In Stock*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC203293 protein sequence
Red=Cloning site Green=Tags(s)

MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGLCAVCLLILSPFWGLILFSVSCFLMYT
YLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQMDIT
KPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKS
KGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLE
KDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSPFAYYTPGKGAYLWICL
AHYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 42.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002144
Locus ID 3294
UniProt ID P37059
Cytogenetics 16q23.3
RefSeq Size 1451
RefSeq ORF 1161
Synonyms EDH17B2; HSD17; SDR9C2
Summary Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Androgen and estrogen metabolism, Metabolic pathways
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "HSD17B2" proteins (3)
SKU Description Size Price
PH303293 HSD17B2 MS Standard C13 and N15-labeled recombinant protein (NP_002144) 10 ug
$3,360.00
LC419500 Lyophilized HSD17B2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419500 Transient overexpression lysate of hydroxysteroid (17-beta) dehydrogenase 2 (HSD17B2) (as WB positive control) 100 ug
$436.00

file-alt Citations

Discovery of the first-in-class highly potent FXR/HSD17B13 dual modulator for the treatment of metabolic dysfunction-associated steatohepatitis
Xu, Liu, Yang et al
Bioorg Chem (2026) 176, 109843 DOI: 10.1016/j.bioorg.2026.109843
AI Summary: OriGene products—recombinant HSD17B2 (TP303293), HSD17B11 (TP305941), and HSD17B14 (TP302531)—were used to assess the inhibitory effects of compounds on these enzymes, supporting the evaluation of selectivity and potency of the novel FXR/HSD17B13 dual modulator described in the study.
Snippet: The method for determining the inhibitory of compounds on HSD17B2 (Origene TP303293), HSD17B11 (Origene TP305941), and HSD17B14 (Origene TP302531) was the same as described above. But the final concentrations of recombinant
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products