hnRNP K(HNRNPK) (NM_002140) Human Recombinant Protein

CAT#: TP301843

Recombinant protein of human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 1

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 Product Datasheet for 'TP301843'

USD 680.00

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    • 20 ug

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Product Data
Description Recombinant protein of human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 1
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC201843. Click on the TrueORF clone link to view cDNA and protein sequences.
Predicted MW 50.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Bioactivity HNRNPK Activity verified in a DNA-binding assay:
Reference Data
RefSeq NP_002131
Locus ID 3190
Refseq Size 2830
Cytogenetics 9q21.32
Refseq ORF 1392
Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008]
Protein Pathways
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