LEPRE1 (P3H1) (NM_022356) Human Mass Spec Standard

SKU PH322535

LEPRE1 MS Standard C13 and N15-labeled recombinant protein (NP_071751)

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: [RC222535]
• Predicted MW: 83.2 kDa
• Protein Sequence:
  Protein Sequence

  RC222535
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_071751
• RefSeq Size: 2993
• RefSeq ORF: 2208
• Synonyms: GROS1; LEPRE1; OI8
• Locus ID: 64175
• UniProt ID: Q32P28
• Cytogenetics: 1p34.2
• Summary: This gene encodes an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly. Mutations in this gene are associated with osteogenesis imperfecta type VIII. Three alternatively spliced transcript variants encoding different isoforms have been described. Other variants may exist, but their biological validity has not been determined. [provided by RefSeq, Aug 2011]
• Protein Families: Secreted Protein