MICB (NM_005931) Human Mass Spec Standard

SKU
PH322315
MICB MS Standard C13 and N15-labeled recombinant protein (NP_005922)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222315
Predicted MW 42.4 kDa
Protein Sequence
Protein Sequence
>RC222315 representing NM_005931
Red=Cloning site Green=Tags(s)

MGLGRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQG
QWAEDVLGAETWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELF
LSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVN
VTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRF
TCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLD
QHPVGTGDHRDAAQLGFQPLMSATGSTGSTEGA

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_005922
RefSeq Size 2385
RefSeq ORF 1149
Synonyms PERB11.2
Locus ID 4277
UniProt ID Q29980
Cytogenetics 6p21.33
Summary This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2014
Protein Families Druggable Genome
Protein Pathways Natural killer cell mediated cytotoxicity
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Other "MICB" proteins (3)
SKU Description Size Price
LC416972 Lyophilized MICB HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416972 Transient overexpression lysate of MHC class I polypeptide-related sequence B (MICB) (as WB positive control) 100 ug
$436.00
TP322315 Recombinant protein of human MHC class I polypeptide-related sequence B (MICB), 20 µg 20 ug
$737.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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