Synapsin III (SYN3) (NM_003490) Human Mass Spec Standard

SKU
PH319395
SYN3 MS Standard C13 and N15-labeled recombinant protein (NP_003481)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219395
Predicted MW 63.1 kDa
Protein Sequence
Protein Sequence
>RC219395 representing NM_003490
Red=Cloning site Green=Tags(s)

MNFLRRRLSDSSFMANLPNGYMTDLQRPDSSTSSPASPAMERRHPQPLAASFSSPGSSLFSSLSSAMKQA
PQATSGLMEPPGPSTPIVQRPRILLVIDDAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCM
VDMQVVRNGTKVVSRSFKPDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQ
LIKIFHSLGPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKTY
ATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICA
VKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQLPMPGGTAPSPLRPWAPQIKSAKSP
GQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPLSPQSGSPQQQRSPGSPQLSRA
SSGSSPNQASKPGATLASQPRPPVQGRSTSQQGEESKKPAPPHPHLNKSQSLTNSLSTSDTSQRGTPSED
EAKAETIRNLRKSFASLFSD

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_003481
RefSeq Size 2918
RefSeq ORF 1740
Locus ID 8224
UniProt ID O14994
Cytogenetics 22q12.3
Summary This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms. provided by RefSeq, Oct 2008
Protein Families Secreted Protein
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Other "Synapsin III" proteins (5)
SKU Description Size Price
LC401178 Lyophilized SYN3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC408773 Lyophilized SYN3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401178 Transient overexpression lysate of synapsin III (SYN3), transcript variant IIIa (as WB positive control) 100 ug
$665.00
LY408773 Transient overexpression lysate of synapsin III (SYN3), transcript variant IIIc (as WB positive control) 100 ug
$665.00
TP319395 Recombinant protein of human synapsin III (SYN3), transcript variant IIIa, 20 µg 20 ug
$737.00

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