GCSH (NM_004483) Human Mass Spec Standard

SKU
PH317886
GCSH MS Standard C13 and N15-labeled recombinant protein (NP_004474)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217886
Predicted MW 18.91 kDa
Protein Sequence
Protein Sequence
>RC217886 representing NM_004483
Red=Cloning site Green=Tags(s)

MALRVVRSVRALLCTLRAVPLPAAPCPPRPWQLGVGAVRTLRTGPALLSVRKFTEKHEWVTTENGIGTVG
ISNFAQEALGDVVYCSLPEVGTKLNKQDEFGALESVKAASELYSPLSGEVTEINEALAENPGLVNKSCYE
DGWLIKMTLSNPSELDELMSEEAYEKYIKSIEE

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_004474
RefSeq Size 1161
RefSeq ORF 519
Synonyms GCE; NKH
Locus ID 2653
UniProt ID P23434
Cytogenetics 16q23.2
Summary Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.provided by RefSeq, Jan 2010
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Other "GCSH" proteins (3)
SKU Description Size Price
LC417961 Lyophilized GCSH HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY417961 Transient overexpression lysate of glycine cleavage system protein H (aminomethyl carrier) (GCSH), nuclear gene encoding mitochondrial protein, transcript variant 1 (as WB positive control) 100 ug
$436.00
TP317886 Recombinant protein of human glycine cleavage system protein H (aminomethyl carrier) (GCSH), 20 µg 20 ug
$737.00

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