VKORC1 (NM_206824) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC214831 |
| Predicted MW | 9.7 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_996560 |
| RefSeq Size | 907 |
| RefSeq ORF | 276 |
| Synonyms | EDTP308; MST134; MST576; VKCFD2; VKOR |
| Locus ID | 79001 |
| UniProt ID | Q9BQB6 |
| Cytogenetics | 16p11.2 |
| Summary | This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2015 |
| Protein Families | Transmembrane |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "VKORC1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC402968 | Lyophilized VKORC1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY402968 | Transient overexpression lysate of vitamin K epoxide reductase complex, subunit 1 (VKORC1), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP314831 | Recombinant protein of human vitamin K epoxide reductase complex, subunit 1 (VKORC1), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
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