VKORC1 (NM_206824) Human Mass Spec Standard

SKU
PH314831
VKORC1 MS Standard C13 and N15-labeled recombinant protein (NP_996560)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC214831
Predicted MW 9.7 kDa
Protein Sequence
Protein Sequence
>RC214831 representing NM_206824
Red=Cloning site Green=Tags(s)

MGSTWGSPGWVRLALCLTGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRLPADTLGLCPDA
AELPGVSRWFCLPGLDPVLRAL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_996560
RefSeq Size 907
RefSeq ORF 276
Synonyms EDTP308; MST134; MST576; VKCFD2; VKOR
Locus ID 79001
UniProt ID Q9BQB6
Cytogenetics 16p11.2
Summary This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2015
Protein Families Transmembrane
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Other "VKORC1" proteins (3)
SKU Description Size Price
LC402968 Lyophilized VKORC1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402968 Transient overexpression lysate of vitamin K epoxide reductase complex, subunit 1 (VKORC1), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP314831 Recombinant protein of human vitamin K epoxide reductase complex, subunit 1 (VKORC1), transcript variant 2, 20 µg 20 ug
$867.00

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