MALT1 (NM_006785) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC214639 |
| Predicted MW | 92.1 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_006776 |
| RefSeq Size | 5029 |
| RefSeq ORF | 2472 |
| Synonyms | IMD12; MLT; MLT1; PCASP1 |
| Locus ID | 10892 |
| UniProt ID | Q9UDY8 |
| Cytogenetics | 18q21.32 |
| Summary | This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus BIRC3(API2)-MALT1, and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. provided by RefSeq, May 2018 |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | B cell receptor signaling pathway, T cell receptor signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "MALT1" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH304322 | MALT1 MS Standard C13 and N15-labeled recombinant protein (NP_776216) | 10 ug |
$3,360.00
|
|
| LC402030 | Lyophilized MALT1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC406281 | Lyophilized MALT1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY402030 | Transient overexpression lysate of mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY406281 | Transient overexpression lysate of mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP304322 | Purified recombinant protein of Homo sapiens mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
| TP314639 | Recombinant protein of human mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
Citations
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