ARNT2 (NM_014862) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC211966 |
| Predicted MW | 78.5 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_055677 |
| RefSeq Size | 6576 |
| RefSeq ORF | 2151 |
| Synonyms | bHLHe1; WEDAS |
| Locus ID | 9915 |
| UniProt ID | Q9HBZ2 |
| Cytogenetics | 15q25.1 |
| Summary | This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. provided by RefSeq, Dec 2013 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Pathways in cancer, Renal cell carcinoma |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "ARNT2" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC402381 | Lyophilized ARNT2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY402381 | Transient overexpression lysate of aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2) (as WB positive control) | 100 ug |
$665.00
|
|
| TP311966 | Recombinant protein of human aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2), 20 µg | 20 ug |
$867.00
|
|
Citations
Analysis of the SIM1 contribution to polygenic obesity in the French population
Ghoussaini, Stutzmann, Couturier et al
Obesity (Silver Spring) (2010) 18 (8), 1670-5 DOI: 10.1038/oby.2009.468
Ghoussaini, Stutzmann, Couturier et al
Obesity (Silver Spring) (2010) 18 (8), 1670-5 DOI: 10.1038/oby.2009.468
Cited by 16
AI Summary: OriGene products contributed to this study through the use of the SIM1 cDNA clone (OriGene, SC119795), which was employed for sequencing and variant analysis of the SIM1 gene in obese and control subjects.
Showing 1-1 of 1 papers.
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