ACMSD (NM_138326) Human Mass Spec Standard

SKU
PH310656
ACMSD MS Standard C13 and N15-labeled recombinant protein (NP_612199)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210656
Predicted MW 38 kDa
Protein Sequence
Protein Sequence
>RC210656 protein sequence
Red=Cloning site Green=Tags(s)

MKIDIHSHILPKEWPDLKKRFGYGGWVQLQHHSKGEAKLLKDGKVFRVVRENCWDPEVRIREMDQKGVTV
QALSTVPVMFSYWAKPEDTLNLCQLLNNDLASTVVSYPRRFVGLGTLPMQAPELAVKEMERCVKELGFPG
VQIGTHVNEWDLNAQELFPVYAAAERLKCSLFVHPWDMQMDGRMAKYWLPWLVGMPAETTIAICSMIMGG
VFEKFPKLKVCFAHGGGAFPFTVGRISHGFSMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDV
IGKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGNALAFLGLERKQFE

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_612199
RefSeq Size 1278
RefSeq ORF 1008
Locus ID 130013
UniProt ID Q8TDX5
Cytogenetics 2q21.3
Summary The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.supplied by OMIM, Oct 2004
Protein Families Transmembrane
Protein Pathways Metabolic pathways, Tryptophan metabolism
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Other "ACMSD" proteins (3)
SKU Description Size Price
LC408707 Lyophilized ACMSD HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY408707 Transient overexpression lysate of aminocarboxymuconate semialdehyde decarboxylase (ACMSD) (as WB positive control) 100 ug
$436.00
TP310656 Recombinant protein of human aminocarboxymuconate semialdehyde decarboxylase (ACMSD), 20 µg 20 ug
$737.00

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