UBE2L3 (NM_003347) Human Mass Spec Standard

SKU
PH308780
UBE2L3 MS Standard C13 and N15-labeled recombinant protein (NP_003338)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208780
Predicted MW 17.9 kDa
Protein Sequence
Protein Sequence
>RC208780 protein sequence
Red=Cloning site Green=Tags(s)

MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITF
KTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNA
EEFTKKYGEKRPVD

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_003338
RefSeq Size 3028
RefSeq ORF 462
Synonyms E2-F1; L-UBC; UBCH7; UbcM4
Locus ID 7332
UniProt ID P68036
Cytogenetics 22q11.21
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Sep 2009
Protein Pathways Parkinson's disease, Ubiquitin mediated proteolysis
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Other "UBE2L3" proteins (3)
SKU Description Size Price
LC401144 Lyophilized UBE2L3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401144 Transient overexpression lysate of ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP308780 Recombinant protein of human ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 1, 20 µg 20 ug
$867.00

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