PKC delta (PRKCD) (NM_212539) Human Mass Spec Standard

SKU
PH308127
PRKCD MS Standard C13 and N15-labeled recombinant protein (NP_997704)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208127
Predicted MW 77.5 kDa
Protein Sequence
Protein Sequence
>RC208127 protein sequence
Red=Cloning site Green=Tags(s)

MAPFLRIAFNSYELGSLQAEDEANQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKSTFDAHIYEGRVIQ
IVLMRAAEEPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMSVQYFLEDVDCKQSMRSEDEAKFP
TMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTG
TAANSRDTIFQKERFNIDMPHRFKVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLC
GINQKLLAEALNQVTQRASRRSDSASSEPVGIYQGFEKKTGVAGEDMQDNSGTYGKIWEGSSKCNINNFI
FHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAENPFLTHLICTFQTK
DHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIA
DFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESI
RVDTPHYPRWITKESKDILEKLFEREPTKRLGVTGNIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDY
SNFDQEFLNEKARLSYSDKNLIDSMDQSAFAGFSFVNPKFEHLLED

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_997704
RefSeq Size 2738
RefSeq ORF 2028
Synonyms ALPS3; CVID9; MAY1; nPKC-delta; PKCD
Locus ID 5580
UniProt ID Q05655
Cytogenetics 3p21.1
Summary The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrome. provided by RefSeq, Aug 2017
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Chemokine signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, GnRH signaling pathway, Neurotrophin signaling pathway, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "PKC delta" proteins (5)
SKU Description Size Price
LC403724 Lyophilized PRKCD HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC416774 Lyophilized PRKCD HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403724 Transient overexpression lysate of protein kinase C, delta (PRKCD), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY416774 Transient overexpression lysate of protein kinase C, delta (PRKCD), transcript variant 1 (as WB positive control) 100 ug
$665.00
TP308127 Recombinant protein of human protein kinase C, delta (PRKCD), transcript variant 2, 20 µg 20 ug
$867.00

file-alt Citations

Multiple suppression pathways of canonical Wnt signalling control thymic epithelial senescence
Varecza, Kvell, Talabér et al
Mech. Ageing Dev. (2011) 132 (5), 249-56 DOI: 10.1016/j.mad.2011.04.007
Cited by 40
AI Summary: In this study, OriGene’s Wnt-4 cDNA clone was used to investigate the role of Wnt-4 in thymic epithelial cell signalling and senescence.
Snippet: threonin kinase can phosphorylate and therefore activate Dvls (Kinoshita et al., 2003) to relay ligand induced signals towards down-stream elements ... Wnt-4 was purchased and subcloned from a commercially available vector (Origene), while the full length PKCδ was a kind gift
FigureFigureFigure
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products