Arginase 1 (ARG1) (NM_000045) Human Mass Spec Standard

SKU
PH304649
ARG1 MS Standard C13 and N15-labeled recombinant protein (NP_000036)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204649
Predicted MW 34.7 kDa
Protein Sequence
Protein Sequence
>RC204649 protein sequence
Red=Cloning site Green=Tags(s)

MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNP
RSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNL
HGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGK
VMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNP
SLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_000036
RefSeq Size 1475
RefSeq ORF 966
Locus ID 383
UniProt ID P05089
Cytogenetics 6q23.2
Summary Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Sep 2011
Protein Families Druggable Genome
Protein Pathways Arginine and proline metabolism, Metabolic pathways
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Other "Arginase 1" proteins (4)
SKU Description Size Price
LC424951 Lyophilized ARG1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY424951 Transient overexpression lysate of arginase, liver (ARG1) (as WB positive control) 100 ug
$436.00
TP304649 Recombinant protein of human arginase, liver (ARG1), 20 µg 20 ug
$737.00
TP721013 Purified recombinant protein of Human arginase, liver (ARG1) 10 ug
$340.00

file-alt Citations

The Role of Arginine Metabolism in Oral Tongue Squamous Cell Carcinoma
Leung, Lau, Liu et al
Cancers (Basel) (2021) 13 (23) DOI: 10.3390/cancers13236068
Cited by 8
AI Summary: OriGene’s ARG1 overexpression plasmid (Cat# RC200307) was used to upregulate ARG1 in oral cancer cells, enabling the study of how altered arginine metabolism affects cell proliferation, invasion, and gene expression in oral tongue squamous cell carcinoma.
FigureFigureFigure
Showing 1-1 of 1 papers.
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