STK3 (NM_006281) Human Mass Spec Standard

SKU
PH303897
STK3 MS Standard C13 and N15-labeled recombinant protein (NP_006272)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203897
Predicted MW 56.3 kDa
Protein Sequence
Protein Sequence
>RC203897 protein sequence
Red=Cloning site Green=Tags(s)

MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKE
ISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFM
RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT
SIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKN
AKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDELDSHTMVKTSVESVGTMRATSTMSEGAQTM
IEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCNQNMHEPFPM
SKNVFPDNWKVPQDGDFDFLKNLSLEELQMRLKALDPMMEREIEELRQRYTAKRQPILDAMDAKKRRQQN
F

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_006272
RefSeq Size 2828
RefSeq ORF 1473
Synonyms KRS1; MST2
Locus ID 6788
UniProt ID Q13188
Cytogenetics 8q22.2
Summary This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jan 2012
Protein Families Druggable Genome, Protein Kinase
Protein Pathways MAPK signaling pathway
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Resources
Other "STK3" proteins (3)
SKU Description Size Price
LC401892 Lyophilized STK3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401892 Transient overexpression lysate of serine/threonine kinase 3 (STE20 homolog, yeast) (STK3) (as WB positive control) 100 ug
$436.00
TP303897 Recombinant protein of human serine/threonine kinase 3 (STE20 homolog, yeast) (STK3), 20 µg 20 ug
$867.00

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