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PEN2 (PSENEN) (NM_172341) Human Mass Spec Standard

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SKU
PH303272
PSENEN MS Standard C13 and N15-labeled recombinant protein (NP_758844)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA306368 Rabbit Polyclonal PEN2 Antibody
100 ug
$640.00
LY403539 Transient overexpression lysate of presenilin enhancer 2 homolog (C. elegans) (PSENEN) (as WB positive control) 100 ug
$436.00

Other products for "PEN2 or NM_172341"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203272
Predicted MW 12 kDa
Protein Sequence
Protein Sequence
>RC203272 protein sequence
Red=Cloning site Green=Tags(s)

MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFLVPAYTEQSQIKGYVWRSAVGFLFWVIV
LTSWITIFQIYRPRWGALGDYLSFTIPLGTP

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_758844
RefSeq Size 834
RefSeq ORF 303
Synonyms ACNINV2; MDS033; MSTP064; PEN-2; PEN2
Locus ID 55851
UniProt ID Q9NZ42
Cytogenetics 19q13.12
Summary Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2013
Protein Families Druggable Genome, Transmembrane
Protein Pathways Alzheimer's disease, Notch signaling pathway
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Other "PEN2" proteins (3)
SKU Description Size Price
LC403539 Lyophilized PSENEN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403539 Transient overexpression lysate of presenilin enhancer 2 homolog (C. elegans) (PSENEN) (as WB positive control) 100 ug
$436.00
TP303272 Recombinant protein of human presenilin enhancer 2 homolog (C. elegans) (PSENEN), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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