GPATCH3 (NM_022078) Human Mass Spec Standard

SKU
PH303010
GPATCH3 MS Standard C13 and N15-labeled recombinant protein (NP_071361)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203010
Predicted MW 59.3 kDa
Protein Sequence
Protein Sequence
>RC203010 protein sequence
Red=Cloning site Green=Tags(s)

MAVPGEAEEEATVYLVVSGIPSVLRSAHLRSYFSQFREERGGGFLCFHYRHRPERAPPQAAPNSALIPTD
PAAEGQLLSQTSATDVRPLSTRDSTPIQTRTCCCVISVRGLAQAQRLIRMYSGRRWLDSHGTWLPGRCLI
RRLRLPTEASGLGSFPFKTRKELQSWKAENEAFTLADLKQLPELNPPVLMPRGNVGTPLRVFLELIRACR
LPPRIITQLQLQFPKTGSSRRYGNVPFEYEDSETVEQEELVYTAEGEEIPQGTYLADIPASPCGEPEEEV
GKEEEEESHSDEDDDRGEEWERHEALHEDVTGQERTTEQLFEEEIELKWEKGGSGLVFYTDAQFWQEEEG
DFDEQTADDWDVDMSVYYDRDGGDKDARDSVQMRLEQRLRDGQEDGSVIERQVGTFERHTKGIGRKVMER
QGWAEGQGLGCRCSGVPEALDSDGQHPRCKRGLGYHGEKLQPFGQLKRPRRNGLGLISTIYDEPLPQDQT
ESLLRRQPPTSMKFRTDMAFVRGSSCASDSPSLPD

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_071361
RefSeq Size 2145
RefSeq ORF 1575
Synonyms GPATC3
Locus ID 63906
UniProt ID Q96I76
Cytogenetics 1p36.11
Summary Involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development (PubMed:28397860). Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6 (PubMed:28414768).UniProtKB/Swiss-Prot Function
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Other "GPATCH3" proteins (3)
SKU Description Size Price
LC411801 Lyophilized GPATCH3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY411801 Transient overexpression lysate of G patch domain containing 3 (GPATCH3) (as WB positive control) 100 ug
$436.00
TP303010 Recombinant protein of human G patch domain containing 3 (GPATCH3), 20 µg 20 ug
$867.00

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