KREMEN2 (NM_024507) Human Mass Spec Standard

SKU
PH302558
KREMEN2 MS Standard C13 and N15-labeled recombinant protein (NP_078783)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202558
Predicted MW 44.4 kDa
Protein Sequence
Protein Sequence
>RC202558 protein sequence
Red=Cloning site Green=Tags(s)

MGTQALQGFLFLLFLPLLQPRGASAGSLHSPGLSECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHS
YSSASDPHGRWGLGAHNFCRNPDGDVQPWCYVAETEEGIYWRYCDIPSCHMPGYLGCFVDSGAPPALSGP
SGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRLAPATDCDQICFGHPGQLCGGDGRLG
VYEVSVGSCQGNWTAPQGVIYSPDFPDEYGPDRNCSWALGPPGAALELTFRLFELADPRDRLELRDAASG
SLLRAFDGARPPPSGPLRLGTAALLLTFRSDARGHAQGFALTYRGLQDAAEDPEAPEGSAQTPAAPLDGA
NVSCSPRPGAPPAAIGGAVCWLREKGPRRWGLPGAPGEAGLCGTNSPEGWPCPAPPGTPRLRVLPRATGL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_078783
RefSeq Size 1989
RefSeq ORF 1260
Synonyms KRM2
Locus ID 79412
UniProt ID Q8NCW0
Cytogenetics 16p13.3
Summary This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. provided by RefSeq, Dec 2011
Protein Families Druggable Genome, Transmembrane
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Other "KREMEN2" proteins (3)
SKU Description Size Price
LC402993 Lyophilized KREMEN2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402993 Transient overexpression lysate of kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP302558 Recombinant protein of human kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2, 20 µg 20 ug
$737.00

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