Cortactin (CTTN) (NM_138565) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC201111 |
| Predicted MW | 57.5 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_612632 |
| RefSeq Size | 3208 |
| RefSeq ORF | 1539 |
| Synonyms | EMS1 |
| Locus ID | 2017 |
| UniProt ID | Q14247 |
| Cytogenetics | 11q13.3 |
| Summary | This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. provided by RefSeq, May 2010 |
| Protein Families | Druggable Genome |
| Protein Pathways | Pathogenic Escherichia coli infection, Tight junction |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Cortactin" proteins (8)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC403359 | Lyophilized CTTN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC417430 | Lyophilized CTTN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC429248 | Lyophilized CTTN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403359 | Transient overexpression lysate of cortactin (CTTN), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY417430 | Transient overexpression lysate of cortactin (CTTN), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY429248 | Transient overexpression lysate of cortactin (CTTN), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP301111 | Recombinant protein of human cortactin (CTTN), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
| TP710315 | Purified recombinant protein of Human cortactin (CTTN / EMS1), transcript variant 2, full length, with C-terminal DDK tag, expressed in sf9, 20ug | 20 ug |
$540.00
|
|
Citations
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