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Mps1 (TTK) (NM_003318) Human Mass Spec Standard

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SKU
PH300093
TTK MS Standard C13 and N15-labeled recombinant protein (NP_003309)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA811813 TTK mouse monoclonal antibody,clone OTI13E9 100 ul
$447.00
LY418762 Transient overexpression lysate of TTK protein kinase (TTK), transcript variant 1 (as WB positive control) 100 ug
$436.00

Other products for "Mps1 or NM_003318"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200093
Predicted MW 97 kDa
Protein Sequence
Protein Sequence
>Peptide sequence encoded by RC200093
Blue=ORF Red=Cloning site Green=Tag(s)

MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLL
LKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARAN
CKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEMLEIALRNLNLQKKQLLSEEEKKNLSAST
VLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPV
NLLNSPDCDVKTDDSVVPCFMKRQTSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKS
SELIITDSITLKNKTESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELAR
KVNTEQKHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQLST
PYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAI
KYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDP
WERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDSQVGTVNYM
PPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDI
PEKDLQDVLKCGLKRDPKQRISIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKA
AKTLYEHYSGGESHNSSSSKTFEKKRGKK
TRTRPLEQKLISEEDLAANDILDYKDDDDKV

Recombinant protein using RC200093 also available, TP300093
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_003309
RefSeq Size 3010
RefSeq ORF 2571
Synonyms CT96; ESK; MPH1; MPS1; MPS1L1; PYT
Locus ID 7272
UniProt ID P33981
Cytogenetics 6q14.1
Summary This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. provided by RefSeq, Nov 2009
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Cell cycle, Oocyte meiosis, TGF-beta signaling pathway, Ubiquitin mediated proteolysis, Wnt signaling pathway
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Other "Mps1" proteins (3)
SKU Description Size Price
LC418762 Lyophilized TTK HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418762 Transient overexpression lysate of TTK protein kinase (TTK), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP300093 Recombinant protein of human TTK protein kinase (TTK), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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