LDL Receptor (LDLR) (NM_000527) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC200006 |
| Predicted MW | 95.38 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000518 |
| RefSeq Size | 5175 |
| RefSeq ORF | 2580 |
| Synonyms | FH; FHC; FHCL1; LDLCQ2 |
| Locus ID | 3949 |
| UniProt ID | P01130 |
| Cytogenetics | 19p13.2 |
| Summary | The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.provided by RefSeq, Sep 2010 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Endocytosis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "LDL Receptor" proteins (8)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC400183 | Lyophilized LDLR HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC434371 | Lyophilized LDLR HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC434377 | Lyophilized LDLR HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400183 | Transient overexpression lysate of low density lipoprotein receptor (LDLR) (as WB positive control) | 100 ug |
$436.00
|
|
| LY434371 | Transient overexpression lysate of low density lipoprotein receptor (LDLR), transcript variant 6 (as WB positive control) | 100 ug |
$665.00
|
|
| LY434377 | Transient overexpression lysate of low density lipoprotein receptor (LDLR), transcript variant 4 (as WB positive control) | 100 ug |
$665.00
|
|
| TP300006 | Recombinant protein of human low density lipoprotein receptor (LDLR), 20 µg | 20 ug |
$737.00
|
|
| TP720505 | Recombinant protein of human low density lipoprotein receptor (LDLR), Ala22 - Arg788 | 10 ug |
$275.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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