FKLF / KLF11 (KLF11) (NM_001177716) Human Tagged ORF Clone Lentiviral Particle
SKU
RC230174L3V
Lenti ORF particles, KLF11 (Myc-DDK-tagged)-Human Kruppel-like factor 11 (KLF11), transcript variant 2, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | FKLF / KLF11 |
Synonyms | FKLF; FKLF1; MODY7; TIEG2; Tieg3 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC230174).
|
ACCN | NM_001177716 |
ORF Size | 1485 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_001177716.1, NP_001171187.1 |
RefSeq ORF | 1488 bp |
Locus ID | 8462 |
UniProt ID | O14901 |
Cytogenetics | 2p25.1 |
Protein Families | Transcription Factors |
MW | 53.8 kDa |
Summary | The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] |
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