Synaptotagmin 1 (SYT1) (NM_001135806) Human Tagged ORF Clone Lentiviral Particle

SKU RC227252L3V

Lenti ORF particles, SYT1 (Myc-DDK tagged) - Human synaptotagmin I (SYT1), transcript variant 3, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Synaptotagmin 1
• Synonyms: BAGOS; P65; SVP65; SYT
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC227252).
• ACCN: NM_001135806
• ORF Size: 1266 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001135806.1, NP_001129278.1
• RefSeq ORF: 1269 bp
• Locus ID: 6857
• UniProt ID: P21579
• Cytogenetics: 12q21.2
• Protein Families: Secreted Protein, Transmembrane
• MW: 47.4 kDa
• Summary: The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM, Jul 2010]