NLRP7 (NM_001127255) Human Tagged ORF Clone Lentiviral Particle

SKU RC226306L4V

Lenti ORF particles, NLRP7 (mGFP-tagged)-Human NLR family, pyrin domain containing 7 (NLRP7), transcript variant 3, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: NLRP7
• Synonyms: CLR19.4; HYDM; NALP7; NOD12; PAN7; PYPAF3
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC226306).
• ACCN: NM_001127255
• ORF Size: 3111 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001127255.1, NP_001120727.1
• RefSeq ORF: 3114 bp
• Locus ID: 199713
• UniProt ID: Q8WX94
• Cytogenetics: 19q13.42
• MW: 118.1 kDa
• Summary: This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]