NLRP7 Rabbit Polyclonal Antibody

SKU TA350981

Rabbit Polyclonal Anti-NLRP7 Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 100-300; Positive control: Human gasrtic cancer; Predicted cell location: Cytoplasm or Nucleus
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human NLRP7
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: NLR family, pyrin domain containing 7
• Database Link:
  NP_996611
  Q8WX94
• Background: This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Synonyms: CLR19.4; HYDM; NALP7; NOD12; PAN7; PYPAF3

Reference Data