APBA2 (NM_001130414) Human Tagged ORF Clone Lentiviral Particle

SKU RC226123L3V

Lenti ORF particles, APBA2 (Myc-DDK-tagged)-Human amyloid beta (A4) precursor protein-binding, family A, member 2 (APBA2), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: APBA2
• Synonyms: D15S1518E; HsT16821; LIN-10; MGC:14091; MINT2; X11-BETA; X11L
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC226123).
• ACCN: NM_001130414
• ORF Size: 2211 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001130414.1, NP_001123886.1
• RefSeq Size: 3617 bp
• RefSeq ORF: 2214 bp
• Locus ID: 321
• UniProt ID: Q99767
• Cytogenetics: 15q13.1
• MW: 81.1 kDa
• Summary: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017]