Heme oxygenase 2 (HMOX2) (NM_001127206) Human Tagged ORF Clone Lentiviral Particle

SKU RC225453L3V

Lenti ORF particles, HMOX2 (Myc-DDK-tagged)-Human heme oxygenase (decycling) 2 (HMOX2), transcript variant 4, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Heme oxygenase 2
• Synonyms: HO-2
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC225453).
• ACCN: NM_001127206
• ORF Size: 948 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001127206.1
• RefSeq Size: 1751 bp
• RefSeq ORF: 951 bp
• Locus ID: 3163
• UniProt ID: P30519
• Cytogenetics: 16p13.3
• Protein Families: Transmembrane
• Protein Pathways: Porphyrin and chlorophyll metabolism
• MW: 36 kDa
• Summary: Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]